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Additional info for Blood and Tissue Antigens. International Symposium on Blood and Tissue Antigens Held At the University of Michigan Medical Center, September 17-19, 1969

Sample text

A constant association exists between ka and the blood group antigen called M (5,6) and between Ka and another antigen called L (7,8). Recently Ellory and Tucker (8) have reported the exciting observation that treatment of LK erythrocytes with anti-L antiserum dramatically stimulates the cation transport system, effectively conferring HK properties on the LK cell. 51 GEORGE J. BREWER ET AL. Because the erythrocytes of newborn lambs of all genotypes are HK and do not react with M antisera, we felt that a study of the sequential development of adult characteristics in the lamb red cells might shed light on important interrelationships.

Thus, a microbe with A activity would successfully infect type A individuals, and after the epidemic had subsided, the residual population would contain fewer type A individuals, ^hjischel (51) has reviewed the experimental evidence relating to the existence of blood group substance activity in plague and smallpox organisms and finds the evidence in both to be such that serious doubts can be raised as to whether either organism can, on these grounds, be considered as a major selective force in altering blood group trequencies.

A. E. Glynn and E. J. Holborow, Lancet _2, 759 (1956). 43. J. O. Goslings Am. J. Hum. Gen. 21, 360 (1969). 44. H. E. Rosenfield, Prog, in Med. Genetics jL, 120 (1967). 45. H. J. V. Neel, Science 128, 719 (1958). 46. J. Solish and H. Gershowitz, Am. J. Hum. Gen. 21, 23 (1969). 47. J. Whitelaw, L. Grames and M. Antone, Obst, and Gyn. _20, 317 (1962). 48. F. J. Pettenkofer and W. Helmbold, Acta Genet. Stat. Med. 10, 267 (1960). 49. J. Kelso, Southwestern Lore 28, 48 (1962). 50. C M . Otten, Current Anthro.

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